The mspecLINE web application allows researchers to explore relationships between human diseases and parts of the proteome that are detectable using a mass spectrometer. Given a disease, the tool will display proteins and peptides from PeptideAtlas that may be associated with the disease. It will also display relevant literature from MEDLINE. Furthermore, mspecLINE allows researchers to select proteotypic peptides for specific protein targets in a mass spectrometry assay.

Screen capture of the mspecLINE web user interface showing Creutzfeldt-Jakob Syndrome as an example disease.

The mspecLINE web application is freely available for use at the following location:

http://informatics.systemsbiology.net/mspecLINE

mspecLINE is open source software. Binaries and source code are available for download here.